Teratogenic Drug Exposure

What is teratogenic drug exposure? 

Teratogenic drug exposure refers to when a baby is exposed during pregnancy to medications or substances that can interfere with development. This can sometimes lead to birth defects, growth problems, or issues with development. 

How is it diagnosed?

If there has been known exposure to a drug that could be harmful in pregnancy, your healthcare team may recommend extra scans or tests to check how the baby is developing. These may include detailed ultrasound scans or other investigations depending on the timing and type of exposure. 

What causes it?

Some medications and substances can affect a baby’s development if taken at certain stages of pregnancy. Common teratogens include: 

  • Certain anti-epileptic drugs (e.g., valproate) 

  • Retinoids (used for acne) 

  • Some antibiotics or chemotherapy drugs 

  • Alcohol or recreational drugs 

What does it mean for my baby?

It depends on the drug, how much was taken, and when during pregnancy the exposure happened. Some exposures may have no effect, while others could lead to changes in growth, learning, or appearance. Your team will support you with information and testing. 

What happens next?

You may be offered extra scans or specialist referrals depending on the type of drug. Your care team will help monitor your baby’s development and advise you on what to expect after birth. 

Will it happen again?

In future pregnancies, your care team can help you plan safer medication options. If you take regular medication, talk to your doctor before becoming pregnant to find the safest plan for you and your baby.